CPAP Not Working? You Have Options.

A physician-built resource to help you understand and compare FDA-approved hypoglossal nerve stimulators for obstructive sleep apnea

Dr. Ryan Nord, Sleep Surgeon

What Is Obstructive Sleep Apnea?

Obstructive sleep apnea (OSA) is a breathing disorder that occurs during sleep. The upper airway collapses—partially or completely—for repeated periods, causing breathing pauses that can happen a few times an hour or more than once a minute.

During these pauses, blood oxygen levels drop and the nervous system is activated, fragmenting your sleep. The result: even a full night in bed can leave you feeling exhausted.

Why Treatment Matters

Over time, the cycle of breathing pauses, low oxygen, and nervous system activation carries serious health consequences. The most significant include:

3.8× the risk of death from any cause with severe untreated sleep apnea1
2.9× as likely to develop high blood pressure — and up to 4× the odds of atrial fibrillation2
1.7× the risk of developing type 2 diabetes3
1.9× the odds of mild cognitive impairment or dementia4

Sources: 1. Young et al., Sleep 2008 — Wisconsin Sleep Cohort, 18-year follow-up; adjusted HR 3.8 for all-cause mortality with untreated severe OSA (AHI ≥30); cardiovascular mortality HR 5.2. 2. Peppard et al., New England Journal of Medicine 2000 — adjusted OR 2.89 for developing hypertension (AHI ≥15); atrial fibrillation: Mehra et al., Am J Respir Crit Care Med 2006 — OR 4.02 (AHI ≥30). 3. Nagayoshi et al., Sleep Medicine 2016 — adjusted HR 1.71–2.75 for incident type 2 diabetes with severe OSA, 12.8-year follow-up. 4. Yaffe et al., JAMA 2011 — adjusted OR 1.85–2.36 for mild cognitive impairment or dementia (AHI ≥15).

Sleep apnea is a serious medical condition—and treating it effectively can change your long-term health trajectory.

How This Site Helps You

1

Compare

See key differences between Inspire and Genio — what's implanted, nightly routine, MRI considerations, and more

2

Decide

Rate what matters most to you and get a personalized fit score for each device based on your priorities

3

Prepare

Download printable handouts and bring your results to your consultation with a sleep surgeon

What You'll Need

Having this information handy will help you get the most out of the decision tool

Sleep Study Results

Especially your AHI and whether events are obstructive vs central/mixed

CPAP Experience

Whether it works, you're intolerant, or you've failed treatment

Learn more about CPAP →

BMI / Height & Weight

Your approximate body mass index or height and weight measurements

DISE Results

If you've had drug-induced sleep endoscopy, what it showed (if known)

Learn more about DISE →

600+ Inspire Implants

Genio Clinical Investigator

VCU Health

FDA-Sourced Data

Evidence-Based

Ready to Find Your Best Fit?

The decision tool takes about 5 minutes. No login required. Completely anonymous.

This site provides education and decision support only. It does not provide medical advice and does not determine eligibility for any device. Always confirm candidacy and next steps with a qualified sleep clinician or sleep surgeon.

Last updated: July 1, 2026