Understanding Inspire

A closer look at how Inspire works, what the surgery involves, what the research shows, and what life looks like after implantation.

How I Explain Inspire to My Patients

In Dr. Nord’s own words

Dr. Ryan Nord holds an Inspire pulse generator, the implantable device used in hypoglossal nerve stimulation therapy for obstructive sleep apnea.

Inspire is like a pacemaker for your breathing. It’s placed through two small incisions — one in your neck and one in your chest, both on the right side. Through the neck incision, we place a small stimulation cuff around the nerve that controls your tongue. We then tunnel a wire down to the chest, where it connects to the battery that powers the device.

The battery lasts about eleven years and never needs to be recharged. The surgery takes roughly an hour, and it’s outpatient — you go home the same day.

About a month later, once you’re fully healed, we activate the device in the office. You’re given a small remote and taught how to use it. At bedtime, you press a button to turn the device on. It pulses once to let you know it’s working, then delays about thirty minutes so you can fall asleep.

Once the therapy kicks in, Inspire senses your breathing with every breath and gently pulses your tongue forward to keep your airway open. This typically reduces sleep apnea by about 70%. You’ll come in about twice a year to have the device checked, and we’ll do a home sleep study three to four months after surgery to confirm everything is working well.

Ryan Nord, MD
<\!-- end quote-layout -->

What’s Actually Being Implanted?

The current generation of Inspire (Inspire V) has just two components, all hidden beneath the skin.

Inspire V pulse generator next to a quarter for size comparison
The Inspire pulse generator, shown next to a quarter for scale
INSPIRE V — TWO COMPONENTS 1 2 1 Stimulation Cuff Wraps around thehypoglossal nervein the neck NECK INCISION 2 Pulse Generator Battery + brain ofthe system. Sensesbreathing + stimulates CHEST INCISION ~1 hourOutpatient surgery 11 yearsBattery life, no recharging Size of a quarterNothing visible from outside

What Does Recovery Look Like?

Most patients are surprised by how manageable the recovery is. The device stays off during the entire healing period — there's no rush.

RECOVERY TIMELINE 1 Surgery Day~1 hour, outpatientGo home same day 2 Days 1–3Most sorenessOTC pain meds enough 3 Weeks 1–2Feeling significantlybetter, light activity 4 Weeks 2–4Resume normal activityDevice stays OFF ON⚡ 1 MonthActivation Day!Device turned onRemote training Sleep study at 3–4 months confirms therapy is working

Am I a Candidate for Inspire?

Not everyone is a candidate. Here are the general criteria Dr. Nord evaluates — if you meet them, there's a strong chance Inspire will work well for you.

AM I A CANDIDATE Moderate–Severe OSAAHI between 15 and 100(events per hour of sleep) Unable to Use CPAPCan't tolerate the mask,pressure, or it doesn’t work BMI ≤ 32Up to 35 in some cases,better outcomes at lower BMI Low Central ApneasInspire treats obstructiveevents, not central ones Pass DISE ExamAirway anatomy checkedwhile sedated before surgery Age 22+FDA approved for adults22 years and older What is DISE?Drug-Induced Sleep Endoscopy — a brief procedure where I use a small camera to watch your airway while you’resedated. This shows exactly where and how your airway collapses, and whether Inspire is the right fit for you.

What the Data Shows

Inspire is one of the most studied surgical treatments for obstructive sleep apnea. The landmark STAR trial was published in the New England Journal of Medicine in 2014, with results sustained through four-plus years of follow-up.

WHAT THE DATA SHOWS — STAR TRIAL RESULTS 68%AHI ReductionApnea events perhour of sleep 85%Soft or No SnoringReported by bedpartners at 12 months 11 → 6Sleepiness ScoreNormalized daytimealertness (ESS) 4+Years SustainedNo loss of effectover long-term follow-up Apnea Events Per Hour (AHI) 3020100 29.3Before 8.912 Months -68% Bed Partner Snoring Report Before18%Loud snoring After85% soft or no snoring Soft / no snoringLoud snoring Partner leaving bedroom: 30% → 5% Source: STAR Trial, New England Journal of Medicine 2014 — results sustained through 4+ year follow-up

Apnea Reduction

Patients went from an average AHI of 29 down to about 9 at twelve months — a 68% reduction in the number of times the airway closes per hour of sleep. By three years, the average AHI had improved further to under 5.

Snoring

Before surgery, only 18% of bed partners reported soft or no snoring. After twelve months with Inspire, that jumped to 85%. The percentage of bed partners who had to leave the bedroom dropped from 30% down to 5%.

Daytime Sleepiness

Patients’ Epworth Sleepiness Scale scores dropped from 11 (abnormally sleepy) to 6 (normal range) — and stayed there through four years of follow-up.

Quality of Life

Functional quality-of-life scores normalized after surgery and remained stable long-term. 63% of patients reported a clinically meaningful improvement in daily functioning. Over 41,000 patients have been implanted worldwide.

How Inspire Compares to Traditional Sleep Surgery

Inspire doesn’t change your anatomy — it works with your anatomy. Unlike traditional tissue-removing surgeries, the therapy is adjustable and reversible.

INSPIRE VS. TRADITIONAL SLEEP SURGERY TRADITIONAL SURGERY (UPPP)Cuts and Restructures Tissue ApproachRemoves / rearranges tissue Success Rate~50% Reversible?No — permanent changes Adjustable?No Side EffectsPermanent swallowing,voice, and taste changes ReadmissionHigher complication rate INSPIRE THERAPYWorks With Your Anatomy ApproachStimulates existing nerve Success Rate68% Reversible?Yes — can be removed Adjustable?Yes — settings tuned over time Side EffectsTemporary soreness,much lower complication rate ReadmissionSignificantly lower

Living with Inspire

Once you’re up and running, the nightly routine is simple. Press a button at bedtime. Turn it off in the morning. That’s it.

LIVING WITH INSPIRE ☽Nightly RoutinePress the button on yourremote at bedtime.Turn it off in the morning.That’s it. 📋Office VisitsAbout twice a year for adevice check and settingstune-up. We review yourusage data and adjustas needed. 🔋Battery LifeLasts approximately11 yearsNo recharging needed.Quick outpatient swapwhen it runs low. ℹInspire is MRI-compatible for head and extremity scans with specific guidelines.You’ll receive a patient ID card to carry with you.

Ready to Learn More?

Dr. Nord will work with you to determine whether Inspire is the best path to better sleep — and walk you through every step of the process.

Contact Us ← Back to Compare Options

This page is for educational purposes only and does not constitute medical advice. Individual results may vary. Clinical data referenced from the Inspire STAR Trial (Strollo et al., N Engl J Med, 2014) and the ADHERE post-approval registry. Inspire is an FDA-approved device for the treatment of moderate to severe obstructive sleep apnea in patients who meet specific eligibility criteria. Always consult with your physician to determine the best treatment option for your individual needs.